New Jersey - Eastern Pennsylvania - Delaware HERC

This position is represented by SEIU Local 2007 and the collective bargaining agreement between the university and SEIU Local 2007 governs the terms and conditions of employment

The Czechowicz Lab within the Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, in the Department of Pediatrics at Stanford University School of Medicine is seeking a motivated, friendly and well-organized Life Science Technician III to perform basic functions and activities involved in various exciting research projects. This a dynamic and stimulating place to work, focused on excellence in research, education and patient care. The Czechowicz lab is focused on hematopoietic stem cell (HSC) biology and further exploring how HSCs interact with their microenvironment through basic science and translational medicine particularly in bone marrow transplantation with a focus on bone marrow failure syndromes to ultimately improve outcomes for these patients and many others.

Our laboratory has previously conducted pioneering work demonstrating that HSC depletion is a critical component to donor HSC engraftment. We have developed multiple pre-clinical agents that enable safe and targeted HSC conditioning, several of which are turning into promising clinical therapies that are now being tested in patients. We are now using these agents as probes to understand underlying hematopoietic biology and are applying these to the treatment of candidate diseases of great need. We are further augmenting this work with complementary efforts in therapeutic gene modification. We are primarily focused on genetic, cancerous and autoimmune blood and immune diseases, but this work could also potentially be expanded to other organ systems as well.

The lab strives to maintain a highly collaborative, dynamic and positive environment. The Life Science Technician III would be a great addition to the team and help with exciting basic and translational experiments that hopefully will result in exciting new therapies for patients.

Anticipated shifts: day shift M-F, weekends and holidays as needed

Duties include:

* Work with a great deal of independence when assisting the research team with animal (mouse)-based experiments. Coordinate with lab members and adhere to a timeline for animal experiments. Perform basic procedures such as peripheral bleeds and injections and prepare samples for further testing. Perform complex procedures such as bone marrow aspirates (surgical procedure) and interfemoral injections. They will be the key manipulator in the technical set-up and checkpoints of mouse in vivo experiments

* Work with veterinary team to ensure methods and procedures are optimal for health and safety of animals and share them with other members of the lab. Liaise with veterinary staff concerning care of experimental animals. Affix appropriate cards to animal cages to indicate special care concerning weaning and nutrition. Follow-up morbidity reports with veterinary staff. Ensure that animal protocols are updated with all planned experimentation and that these are followed by laboratory team. Alert veterinary staff of abnormal animal physical presentation/behavior

* Keep track of all experimentation in laboratory notebook and keep careful records of all animal use and animal breeding. Discuss this with lab manager and PI to ensure proper use and budgeting.

* Coordinate with lab members regarding general lab maintenance, supply inventory, and safety. Order animal equipment and supplies as needed. Coordinate use of equipment in animal facility.

* Check animal cages at least 3 times per week. Colony maintenance and genotyping. Set-up timed pregnancies for animals as required. At sacrifice, sample tissues and organs so that they are suitable for immunohistochemistry analysis and/or isolated cells according to the experimental needs defined with the PI.

* Train and orient a variety of technicians, students, and research staff in technical procedures and use of equipment. Assign, coordinate, evaluate, and provide guidance to lower-level technicians

The expected pay range for this position is $44.28 to $53.39/ hour.

Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location, and external market pay for comparable jobs. Placement in the pay range is also subject to the applicable Collective Bargaining Agreement.